Cargando…
Endothelial Dysfunction in Fabry Disease Is Related to Glycocalyx Degradation
Fabry disease (FD) is an X-linked multisystemic lysosomal storage disease due to a deficiency of α-galactosidase A (GLA/AGAL). Progressive cellular accumulation of the AGAL substrate globotriaosylceramide (Gb(3)) leads to endothelial dysfunction. Here, we analyzed endothelial function in vivo and in...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670230/ https://www.ncbi.nlm.nih.gov/pubmed/34917096 http://dx.doi.org/10.3389/fimmu.2021.789142 |