Cargando…

Tetrandrine alleviates podocyte injury via calcium-dependent calpain-1 signaling blockade

BACKGROUND: Podocytes have become a crucial target for interventions in proteinuric kidney diseases. Many studies have reported that overexpression of transient receptor potential cation channel protein 6 (TRPC6) in podocyte injury upregulates intracellular Ca(2+) influx and stimulates Ca(2+)-depend...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Yin, Tang, Xuanli, Wang, Yuhui, Yu, Dongrong, Zhu, Caifeng, Yu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670271/
https://www.ncbi.nlm.nih.gov/pubmed/34906112
http://dx.doi.org/10.1186/s12906-021-03469-x