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Tetrandrine alleviates podocyte injury via calcium-dependent calpain-1 signaling blockade
BACKGROUND: Podocytes have become a crucial target for interventions in proteinuric kidney diseases. Many studies have reported that overexpression of transient receptor potential cation channel protein 6 (TRPC6) in podocyte injury upregulates intracellular Ca(2+) influx and stimulates Ca(2+)-depend...
Autores principales: | Ding, Yin, Tang, Xuanli, Wang, Yuhui, Yu, Dongrong, Zhu, Caifeng, Yu, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670271/ https://www.ncbi.nlm.nih.gov/pubmed/34906112 http://dx.doi.org/10.1186/s12906-021-03469-x |
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