TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension

BACKGROUND: Hypoxic pulmonary hypertension (PH) is a refractory pulmonary vascular remodeling disease, and the efficiency of current PH treatment strategies is unsatisfactory. Tribbles homolog 3 (TRB3), a member of the pseudokinase family, is upregulated in diverse types of cellular stresses and fun...

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Detalles Bibliográficos
Autores principales: Cao, Xiaopei, Fang, Xiaoyu, Guo, Mingzhou, Li, Xiaochen, He, Yuanzhou, Xie, Min, Xu, Yongjian, Liu, Xiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670293/
https://www.ncbi.nlm.nih.gov/pubmed/34906150
http://dx.doi.org/10.1186/s12931-021-01908-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670293/
https://www.ncbi.nlm.nih.gov/pubmed/34906150
http://dx.doi.org/10.1186/s12931-021-01908-4

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