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Inhibition of human lung cancer cells by anti-p21Ras scFv mediated by the activatable cell-penetrating peptide
Activatable cell-penetrating peptide (ACPP) is a tumour-targeting cell-penetrating peptide. Here, we used ACPP to carry anti-p21Ras scFv for Ras-driven cancer therapy. The ACPP-p21Ras scFv fusion protein was prepared by a prokaryotic expression system and Ni-NTA column purification. The human tumour...
Autores principales: | Du, Yu, Lin, Xinrui, Feng, Qiang, Pan, Xinyan, Song, Shuling, Yang, Julun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670359/ https://www.ncbi.nlm.nih.gov/pubmed/34338241 http://dx.doi.org/10.1097/CAD.0000000000001180 |
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