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Benchmarking the ideal sample thickness in cryo-EM

The relationship between sample thickness and quality of data obtained is investigated by microcrystal electron diffraction (MicroED). Several electron microscopy (EM) grids containing proteinase K microcrystals of similar sizes from the same crystallization batch were prepared. Each grid was transf...

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Detalles Bibliográficos
Autores principales: Martynowycz, Michael W., Clabbers, Max T. B., Unge, Johan, Hattne, Johan, Gonen, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670461/
https://www.ncbi.nlm.nih.gov/pubmed/34873060
http://dx.doi.org/10.1073/pnas.2108884118