A Functional SNP in the Promoter of LBX1 Is Associated With the Development of Adolescent Idiopathic Scoliosis Through Involvement in the Myogenesis of Paraspinal Muscles

Previous studies have shown that LBX1 is associated with adolescent idiopathic scoliosis (AIS) in multiple populations. For the first time, rs1322330 located in the putative promoter region of LBX1 was found significantly associated with AIS in the Chinese population [p = 6.08 × 10(–14), odds ratio...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Leilei, Feng, Zhenhua, Dai, Zhicheng, Lee, Wayne Y. W., Wu, Zhichong, Liu, Zhen, Sun, Xu, Tang, Nelson, Cheng, Jack Chun-Yiu, Qiu, Yong, Zhu, Zezhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670502/
https://www.ncbi.nlm.nih.gov/pubmed/34917617
http://dx.doi.org/10.3389/fcell.2021.777890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670502/
https://www.ncbi.nlm.nih.gov/pubmed/34917617
http://dx.doi.org/10.3389/fcell.2021.777890

Ejemplares similares