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A Functional SNP in the Promoter of LBX1 Is Associated With the Development of Adolescent Idiopathic Scoliosis Through Involvement in the Myogenesis of Paraspinal Muscles
Previous studies have shown that LBX1 is associated with adolescent idiopathic scoliosis (AIS) in multiple populations. For the first time, rs1322330 located in the putative promoter region of LBX1 was found significantly associated with AIS in the Chinese population [p = 6.08 × 10(–14), odds ratio...
Autores principales: | Xu, Leilei, Feng, Zhenhua, Dai, Zhicheng, Lee, Wayne Y. W., Wu, Zhichong, Liu, Zhen, Sun, Xu, Tang, Nelson, Cheng, Jack Chun-Yiu, Qiu, Yong, Zhu, Zezhang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670502/ https://www.ncbi.nlm.nih.gov/pubmed/34917617 http://dx.doi.org/10.3389/fcell.2021.777890 |
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