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Identification of Inhibitors of Fungal Fatty Acid Biosynthesis

[Image: see text] Fungal fatty acid (FA) synthase and desaturase enzymes are essential for the growth and virulence of human fungal pathogens. These enzymes are structurally distinct from their mammalian counterparts, making them attractive targets for antifungal development. However, there has been...

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Detalles Bibliográficos
Autores principales: DeJarnette, Christian, Meyer, Chris J., Jenner, Alexander R., Butts, Arielle, Peters, Tracy, Cheramie, Martin N., Phelps, Gregory A., Vita, Nicole A., Loudon-Hossler, Victoria C., Lee, Richard E., Palmer, Glen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670506/
https://www.ncbi.nlm.nih.gov/pubmed/34786940
http://dx.doi.org/10.1021/acsinfecdis.1c00404