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Serotonin 2C Antagonism in the Lateral Orbitofrontal Cortex Ameliorates Cue-Enhanced Risk Preference and Restores Sensitivity to Reinforcer Devaluation in Male Rats

Previous research has indicated that reward-paired cues can enhance disadvantageous risky choice in both humans and rodents. Systemic administration of a serotonin 2C receptor antagonist can attenuate this cue-induced risk preference in rats. However, the neurocognitive mechanisms mediating this eff...

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Detalles Bibliográficos
Autores principales: Hathaway, Brett A., Schumacher, Jackson D., Hrelja, Kelly M., Winstanley, Catharine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670605/
https://www.ncbi.nlm.nih.gov/pubmed/34815296
http://dx.doi.org/10.1523/ENEURO.0341-21.2021