Cargando…

Identifying proximal RNA interactions from cDNA-encoded crosslinks with ShapeJumper

SHAPE-JuMP is a concise strategy for identifying close-in-space interactions in RNA molecules. Nucleotides in close three-dimensional proximity are crosslinked with a bi-reactive reagent that covalently links the 2’-hydroxyl groups of the ribose moieties. The identities of crosslinked nucleotides ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Christy, Thomas W., Giannetti, Catherine A., Laederach, Alain, Weeks, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670686/
https://www.ncbi.nlm.nih.gov/pubmed/34905538
http://dx.doi.org/10.1371/journal.pcbi.1009632