Cargando…
Identifying proximal RNA interactions from cDNA-encoded crosslinks with ShapeJumper
SHAPE-JuMP is a concise strategy for identifying close-in-space interactions in RNA molecules. Nucleotides in close three-dimensional proximity are crosslinked with a bi-reactive reagent that covalently links the 2’-hydroxyl groups of the ribose moieties. The identities of crosslinked nucleotides ar...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670686/ https://www.ncbi.nlm.nih.gov/pubmed/34905538 http://dx.doi.org/10.1371/journal.pcbi.1009632 |