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Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans

Genome copy number variation occurs during each mitotic and meiotic cycle and it is crucial for organisms to maintain their natural ploidy. Defects in ploidy transitions can lead to chromosome instability, which is a hallmark of cancer. Ploidy in the haploid human fungal pathogen Cryptococcus neofor...

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Detalles Bibliográficos
Autores principales: Fu, Ci, Davy, Aaliyah, Holmes, Simeon, Sun, Sheng, Yadav, Vikas, Gusa, Asiya, Coelho, Marco A., Heitman, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670703/
https://www.ncbi.nlm.nih.gov/pubmed/34843473
http://dx.doi.org/10.1371/journal.pgen.1009935