Non-microRNA binding competitively inhibits LIN28 regulation

RNA binding protein (RBP) expression is finite. For RBPs that are vastly outnumbered by their potential target sites, a simple competition for binding can set the magnitude of post-transcriptional control. Here, we show that LIN28, best known for its direct regulation of let-7 miRNA biogenesis, is a...

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Detalles Bibliográficos
Autores principales: Tan, Frederick E., Sathe, Shashank, Wheeler, Emily C., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670721/
https://www.ncbi.nlm.nih.gov/pubmed/34380031
http://dx.doi.org/10.1016/j.celrep.2021.109517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670721/
https://www.ncbi.nlm.nih.gov/pubmed/34380031
http://dx.doi.org/10.1016/j.celrep.2021.109517

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