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Radiation-activated secretory proteins of Scgb1a1(+) club cells increase the efficacy of immune checkpoint blockade in lung cancer

Radiation therapy (RT) in combination with immune checkpoint inhibitor (ICI) represents a promising regimen for non-small cell lung cancer (NSCLC), however, the underlying mechanisms are poorly characterized. We identified a specific dose of RT that conferred tumor regression and improved survival i...

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Detalles Bibliográficos
Autores principales: Ban, Yi, Markowitz, Geoffrey J., Zou, Yue, Ramchandani, Divya, Kraynak, Jeffrey, Sheng, Jianting, Lee, Sharrell B., Wong, Stephen T.C., Altorki, Nasser K., Gao, Dingcheng, Mittal, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670735/
https://www.ncbi.nlm.nih.gov/pubmed/34917944
http://dx.doi.org/10.1038/s43018-021-00245-1