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Radiation-activated secretory proteins of Scgb1a1(+) club cells increase the efficacy of immune checkpoint blockade in lung cancer
Radiation therapy (RT) in combination with immune checkpoint inhibitor (ICI) represents a promising regimen for non-small cell lung cancer (NSCLC), however, the underlying mechanisms are poorly characterized. We identified a specific dose of RT that conferred tumor regression and improved survival i...
Autores principales: | Ban, Yi, Markowitz, Geoffrey J., Zou, Yue, Ramchandani, Divya, Kraynak, Jeffrey, Sheng, Jianting, Lee, Sharrell B., Wong, Stephen T.C., Altorki, Nasser K., Gao, Dingcheng, Mittal, Vivek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670735/ https://www.ncbi.nlm.nih.gov/pubmed/34917944 http://dx.doi.org/10.1038/s43018-021-00245-1 |
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