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Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy
Cyclic di-nucleotides (CDNs) are widespread second messenger signalling molecules that regulate fundamental biological processes across the tree of life. These molecules are also potent modulators of the immune system, inducing a Type I interferon response upon binding to the eukaryotic receptor STI...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Royal Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670957/ https://www.ncbi.nlm.nih.gov/pubmed/34905701 http://dx.doi.org/10.1098/rsob.210277 |