Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury

Aims. Acute kidney injury (AKI) can lead to chronic kidney disease (CKD), and macrophages play a key role in this process. The aim of this study was to discover the role of IκB kinase α (IKKα) in macrophages in the process of AKI-to-CKD transition. Main Methods. We crossed lyz2-Cre mice with IKKα-fl...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Feng, Fan, Li, Zhang, Hao, Huang, Wen-juan, Sun, Dong, Pan, Bin-bin, Wan, Xin, Cao, Chang-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670970/
https://www.ncbi.nlm.nih.gov/pubmed/34917688
http://dx.doi.org/10.1155/2021/5521051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670970/
https://www.ncbi.nlm.nih.gov/pubmed/34917688
http://dx.doi.org/10.1155/2021/5521051

Ejemplares similares