A Two-Week Insulin Infusion in Intrauterine Growth Restricted Fetal Sheep at 75% Gestation Increases Skeletal Myoblast Replication but Did Not Restore Muscle Mass or Increase Fiber Number

Intrauterine growth restricted (IUGR) fetuses are born with lower skeletal muscle mass, fewer proliferating myoblasts, and fewer myofibers compared to normally growing fetuses. Plasma concentrations of insulin, a myogenic growth factor, are lower in IUGR fetuses. We hypothesized that a two-week insu...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Eileen I., Hetrick, Byron, Wesolowski, Stephanie R., McCurdy, Carrie E., Rozance, Paul J., Brown, Laura D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670988/
https://www.ncbi.nlm.nih.gov/pubmed/34917036
http://dx.doi.org/10.3389/fendo.2021.785242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670988/
https://www.ncbi.nlm.nih.gov/pubmed/34917036
http://dx.doi.org/10.3389/fendo.2021.785242

Ejemplares similares