Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination

Alternative end joining (A-EJ) catalyzes substantial level of antibody class switch recombination (CSR) in B cells deficient for classical non-homologous end joining, featuring increased switch (S) region DSB resection and junctional microhomology (MH). While resection has been suggested to initiate...

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Detalles Bibliográficos
Autores principales: Sun, Xikui, Bai, Jingning, Xu, Jiejie, Xi, Xiaoli, Gu, Mingyu, Zhu, Chengming, Xue, Hongman, Chen, Chun, Dong, Junchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671047/
https://www.ncbi.nlm.nih.gov/pubmed/34926456
http://dx.doi.org/10.3389/fcell.2021.767624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671047/
https://www.ncbi.nlm.nih.gov/pubmed/34926456
http://dx.doi.org/10.3389/fcell.2021.767624

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