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Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination
Alternative end joining (A-EJ) catalyzes substantial level of antibody class switch recombination (CSR) in B cells deficient for classical non-homologous end joining, featuring increased switch (S) region DSB resection and junctional microhomology (MH). While resection has been suggested to initiate...
Autores principales: | Sun, Xikui, Bai, Jingning, Xu, Jiejie, Xi, Xiaoli, Gu, Mingyu, Zhu, Chengming, Xue, Hongman, Chen, Chun, Dong, Junchao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671047/ https://www.ncbi.nlm.nih.gov/pubmed/34926456 http://dx.doi.org/10.3389/fcell.2021.767624 |
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