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Exploring the translational potential of clusterin as a biomarker of early osteoarthritis

BACKGROUND: Clusterin (CLU; also known as apolipoprotein J) is an ATP-independent holdase chaperone that prevents proteotoxicity as a consequence of protein aggregation. It is a ∼60 kDa disulfide-linked heterodimeric protein involved in the clearance of cellular debris and the regulation of apoptosi...

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Detalles Bibliográficos
Autores principales: Kalvaityte, Ursule, Matta, Csaba, Bernotiene, Eiva, Pushparaj, Peter Natesan, Kiapour, Ata M., Mobasheri, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671091/
https://www.ncbi.nlm.nih.gov/pubmed/34976733
http://dx.doi.org/10.1016/j.jot.2021.10.001