SIRPγ-CD47 Interaction Positively Regulates the Activation of Human T Cells in Situation of Chronic Stimulation

A numerous number of positive and negative signals via various molecules modulate T-cell activation. Within the various transmembrane proteins, SIRPγ is of interest since it is not expressed in rodents. SIRPγ interaction with CD47 is reevaluated in this study. Indeed, we show that the anti-SIRPγ mAb...

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Detalles Bibliográficos
Autores principales: Dehmani, Safa, Nerrière-Daguin, Véronique, Néel, Mélanie, Elain-Duret, Nathan, Heslan, Jean-Marie, Belarif, Lyssia, Mary, Caroline, Thepenier, Virginie, Biteau, Kevin, Poirier, Nicolas, Blancho, Gilles, Haspot, Fabienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671138/
https://www.ncbi.nlm.nih.gov/pubmed/34925315
http://dx.doi.org/10.3389/fimmu.2021.732530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671138/
https://www.ncbi.nlm.nih.gov/pubmed/34925315
http://dx.doi.org/10.3389/fimmu.2021.732530

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