NOTCH4 Exhibits Anti-Inflammatory Activity in Activated Macrophages by Interfering With Interferon-γ and TLR4 Signaling

NOTCH4 is a member of the NOTCH family of receptors whose expression is intensively induced in macrophages after their activation by Toll-like receptors (TLR) and/or interferon-γ (IFN-γ). In this work, we show that this receptor acts as a negative regulator of macrophage activation by diminishing th...

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Detalles Bibliográficos
Autores principales: López-López, Susana, Romero de Ávila, María José, Hernández de León, Natalia Carolina, Ruiz-Marcos, Francisco, Baladrón, Victoriano, Nueda, María Luisa, Laborda, Jorge, García-Ramírez, José Javier, Monsalve, Eva M., Díaz-Guerra, María José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671160/
https://www.ncbi.nlm.nih.gov/pubmed/34925319
http://dx.doi.org/10.3389/fimmu.2021.734966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671160/
https://www.ncbi.nlm.nih.gov/pubmed/34925319
http://dx.doi.org/10.3389/fimmu.2021.734966

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