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NOTCH4 Exhibits Anti-Inflammatory Activity in Activated Macrophages by Interfering With Interferon-γ and TLR4 Signaling
NOTCH4 is a member of the NOTCH family of receptors whose expression is intensively induced in macrophages after their activation by Toll-like receptors (TLR) and/or interferon-γ (IFN-γ). In this work, we show that this receptor acts as a negative regulator of macrophage activation by diminishing th...
Autores principales: | López-López, Susana, Romero de Ávila, María José, Hernández de León, Natalia Carolina, Ruiz-Marcos, Francisco, Baladrón, Victoriano, Nueda, María Luisa, Laborda, Jorge, García-Ramírez, José Javier, Monsalve, Eva M., Díaz-Guerra, María José M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671160/ https://www.ncbi.nlm.nih.gov/pubmed/34925319 http://dx.doi.org/10.3389/fimmu.2021.734966 |
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