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Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects

Several members of the FGF family have been identified as potential regulators of glucose homeostasis. We previously reported that a low threshold of FGF-induced FGF receptor 1c (FGFR1c) dimerization and activity is sufficient to evoke a glucose lowering activity. We therefore reasoned that ligand i...

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Detalles Bibliográficos
Autores principales: Ying, Lei, Wang, Luyao, Guo, Kaiwen, Hou, Yushu, Li, Na, Wang, Shuyi, Liu, Xingfeng, Zhao, Qijin, Zhou, Jie, Zhao, Longwei, Niu, Jianlou, Chen, Chuchu, Song, Lintao, Hou, Shaocong, Kong, Lijuan, Li, Xiaokun, Ren, Jun, Li, Pingping, Mohammadi, Moosa, Huang, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671394/
https://www.ncbi.nlm.nih.gov/pubmed/34907199
http://dx.doi.org/10.1038/s41467-021-27584-y