Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity

Nanocomplexes systems made up natural poylymers have pharmacotechnical advantages such as increase of water solubility and a decrease of drugs toxicity. Amphotericin B (AmB) is a drug apply as anti-leishmanial and anti-fungal, however it has low water solubility and high toxicity, limiting its thera...

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Detalles Bibliográficos
Autores principales: Soeiro, Victória Soares, Silva-Carvalho, Ricardo, Martins, Daniela, Parpot, Pier, Grotto, Denise, Chaud, Marco Vinicius, da Gama, Francisco Miguel Portela, Jozala, Angela Faustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671405/
https://www.ncbi.nlm.nih.gov/pubmed/34907234
http://dx.doi.org/10.1038/s41598-021-03264-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671405/
https://www.ncbi.nlm.nih.gov/pubmed/34907234
http://dx.doi.org/10.1038/s41598-021-03264-1

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