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Identification of mitochondrial RNA polymerase as a potential therapeutic target of osteosarcoma

POLRMT (RNA polymerase mitochondrial) is essential for transcription of mitochondrial genome encoding components of oxidative phosphorylation process. The current study tested POLRMT expression and its potential function in osteosarcoma (OS). The Cancer Genome Atlas (TCGA) cohorts and Gene Expressio...

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Detalles Bibliográficos
Autores principales: Han, Qi-cai, Zhang, Xiang-yang, Yan, Peng-hui, Chen, Song-feng, Liu, Fei-fei, Zhu, Yun-Rong, Tian, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671410/
https://www.ncbi.nlm.nih.gov/pubmed/34907167
http://dx.doi.org/10.1038/s41420-021-00780-x