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Identification of mitochondrial RNA polymerase as a potential therapeutic target of osteosarcoma
POLRMT (RNA polymerase mitochondrial) is essential for transcription of mitochondrial genome encoding components of oxidative phosphorylation process. The current study tested POLRMT expression and its potential function in osteosarcoma (OS). The Cancer Genome Atlas (TCGA) cohorts and Gene Expressio...
Autores principales: | Han, Qi-cai, Zhang, Xiang-yang, Yan, Peng-hui, Chen, Song-feng, Liu, Fei-fei, Zhu, Yun-Rong, Tian, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671410/ https://www.ncbi.nlm.nih.gov/pubmed/34907167 http://dx.doi.org/10.1038/s41420-021-00780-x |
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