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Uncovering drug repurposing candidates for head and neck cancers: insights from systematic pharmacogenomics data analysis

Effective treatment options for head and neck squamous cell carcinoma (HNSCC) are currently lacking. We exploited the drug response and genomic data of the 28 HNSCC cell lines, screened with 4,518 compounds, from the PRISM repurposing dataset to uncover repurposing drug candidates for HNSCC. A total...

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Detalles Bibliográficos
Autores principales: Chai, Annie Wai Yeeng, Tan, Aik Choon, Cheong, Sok Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671460/
https://www.ncbi.nlm.nih.gov/pubmed/34907286
http://dx.doi.org/10.1038/s41598-021-03418-1