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Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling

The stimulatory G-protein alpha subunit (Gsα), a ubiquitously expressed protein, mediates G-protein receptor-stimulated signal transduction. To investigate the functions of Gsα in cardiomyocytes. We developed transverse aortic constriction (TAC)-induced heart failure mouse models and tamoxifen-induc...

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Detalles Bibliográficos
Autores principales: Yin, Ping, Li, Dan, Zhao, Qi, Cai, Mingming, Wu, Zhenru, Shi, Yujun, Su, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671484/
https://www.ncbi.nlm.nih.gov/pubmed/34907172
http://dx.doi.org/10.1038/s41420-021-00788-3