Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy

Antibodies targeting costimulatory receptors of T cells have been developed for the activation of T cell immunity in cancer immunotherapy. However, costimulatory molecule expression is often lacking in tumor-infiltrating immune cells, which can impede antibody-mediated immunotherapy. Here, we hypoth...

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Detalles Bibliográficos
Autores principales: Li, Wenqing, Zhang, Xinfu, Zhang, Chengxiang, Yan, Jingyue, Hou, Xucheng, Du, Shi, Zeng, Chunxi, Zhao, Weiyu, Deng, Binbin, McComb, David W., Zhang, Yuebao, Kang, Diana D., Li, Junan, Carson, William E., Dong, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671507/
https://www.ncbi.nlm.nih.gov/pubmed/34907171
http://dx.doi.org/10.1038/s41467-021-27434-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671507/
https://www.ncbi.nlm.nih.gov/pubmed/34907171
http://dx.doi.org/10.1038/s41467-021-27434-x

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