Pharmacokinetics and central accumulation of delta-9-tetrahydrocannabinol (THC) and its bioactive metabolites are influenced by route of administration and sex in rats

Up to a third of North Americans report using cannabis in the prior month, most commonly through inhalation. Animal models that reflect human consumption are critical to study the impact of cannabis on brain and behaviour. Most animal studies to date utilize injection of delta-9-tetrahydrocannabinol...

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Detalles Bibliográficos
Autores principales: Baglot, Samantha L., Hume, Catherine, Petrie, Gavin N., Aukema, Robert J., Lightfoot, Savannah H. M., Grace, Laine M., Zhou, Ruokun, Parker, Linda, Rho, Jong M., Borgland, Stephanie L., McLaughlin, Ryan J., Brechenmacher, Laurent, Hill, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671514/
https://www.ncbi.nlm.nih.gov/pubmed/34907248
http://dx.doi.org/10.1038/s41598-021-03242-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671514/
https://www.ncbi.nlm.nih.gov/pubmed/34907248
http://dx.doi.org/10.1038/s41598-021-03242-7

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