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Simultaneous estimation of bi-directional causal effects and heritable confounding from GWAS summary statistics
Mendelian Randomisation (MR) is an increasingly popular approach that estimates the causal effect of risk factors on complex human traits. While it has seen several extensions that relax its basic assumptions, most suffer from two major limitations; their under-exploitation of genome-wide markers, a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671515/ https://www.ncbi.nlm.nih.gov/pubmed/34907193 http://dx.doi.org/10.1038/s41467-021-26970-w |