Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates

Regulatory T cells (Tregs) play an important role in controlling inflammation and limiting autoimmunity, but their phenotypes at inflammatory sites in human disease are poorly understood. We here analyze the single-cell transcriptome of >16,000 Tregs obtained from peripheral blood and synovial fl...

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Detalles Bibliográficos
Autores principales: Simone, Davide, Penkava, Frank, Ridley, Anna, Sansom, Stephen, Al-Mossawi, M. Hussein, Bowness, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671562/
https://www.ncbi.nlm.nih.gov/pubmed/34907325
http://dx.doi.org/10.1038/s42003-021-02931-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671562/
https://www.ncbi.nlm.nih.gov/pubmed/34907325
http://dx.doi.org/10.1038/s42003-021-02931-3

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