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Long noncoding RNA GSEC promotes neutrophil inflammatory activation by supporting PFKFB3-involved glycolytic metabolism in sepsis

Metabolic reprogramming is a hallmark of neutrophil activation in sepsis. LncRNAs play important roles in manipulating cell metabolism; however, their specific involvement in neutrophil activation in sepsis remains unclear. Here we found that 11 lncRNAs and 105 mRNAs were differentially expressed in...

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Detalles Bibliográficos
Autores principales: Liu, Dadong, Sun, Wen, Zhang, Danying, Yu, Zongying, Qin, Weiting, Liu, Yishu, Zhang, Kai, Yin, Jiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671582/
https://www.ncbi.nlm.nih.gov/pubmed/34907156
http://dx.doi.org/10.1038/s41419-021-04428-7