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Podocalyxin promotes an impermeable epithelium and inhibits pro-implantation factors to negatively regulate endometrial receptivity

Embryo implantation is a key step in establishing pregnancy and a major limiting factor in IVF. Implantation requires a receptive endometrium but the mechanisms governing receptivity are not well understood. We have recently discovered that podocalyxin (PCX or PODXL) is a key negative regulator of h...

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Detalles Bibliográficos
Autores principales: Heng, Sophea, Samarajeewa, Nirukshi, Wang, Yao, Paule, Sarah G., Breen, James, Nie, Guiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671585/
https://www.ncbi.nlm.nih.gov/pubmed/34907278
http://dx.doi.org/10.1038/s41598-021-03425-2