L-type amino acid transporter (LAT) 1 expression in (18)F-FET-negative gliomas

BACKGROUND: O-(2-[(18)F]-fluoroethyl)-L-tyrosine ((18)F-FET) is a highly sensitive PET tracer for glioma imaging, and its uptake is suggested to be driven by an overexpression of the L-type amino-acid transporter 1 (LAT1). However, 30% of low- and 5% of high-grade gliomas do not present enhanced (18...

Descripción completa

Detalles Bibliográficos
Autores principales: Vettermann, Franziska J., Diekmann, Caroline, Weidner, Lorraine, Unterrainer, Marcus, Suchorska, Bogdana, Ruf, Viktoria, Dorostkar, Mario, Wenter, Vera, Herms, Jochen, Tonn, Jörg-Christian, Bartenstein, Peter, Riemenschneider, Markus J., Albert, Nathalie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671595/
https://www.ncbi.nlm.nih.gov/pubmed/34905134
http://dx.doi.org/10.1186/s13550-021-00865-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671595/
https://www.ncbi.nlm.nih.gov/pubmed/34905134
http://dx.doi.org/10.1186/s13550-021-00865-9

Ejemplares similares