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Alpha-Gal Syndrome: Involvement of Amblyomma americanum α-D-Galactosidase and β-1,4 Galactosyltransferase Enzymes in α-Gal Metabolism

Alpha-Gal Syndrome (AGS) is an IgE-mediated delayed-type hypersensitivity reaction to the oligosaccharide galactose-α-1, 3-galactose (α-gal) injected into humans from the lone-star tick (Amblyomma americanum) bite. Indeed, α-gal is discovered in salivary glands of lone-star tick; however, the tick’s...

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Detalles Bibliográficos
Autores principales: Sharma, Surendra Raj, Crispell, Gary, Mohamed, Ahmed, Cox, Cameron, Lange, Joshua, Choudhary, Shailesh, Commins, Scott P., Karim, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671611/
https://www.ncbi.nlm.nih.gov/pubmed/34926322
http://dx.doi.org/10.3389/fcimb.2021.775371