Cargando…

The mGluR6 ligand-binding domain, but not the C-terminal domain, is required for synaptic localization in retinal ON-bipolar cells

Signals from retinal photoreceptors are processed in two parallel channels—the ON channel responds to light increments, while the OFF channel responds to light decrements. The ON pathway is mediated by ON type bipolar cells (BCs), which receive glutamatergic synaptic input from photoreceptors via a...

Descripción completa

Detalles Bibliográficos
Autores principales: Agosto, Melina A., Adeosun, Abiodun Adefola R., Kumar, Nitin, Wensel, Theodore G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671642/
https://www.ncbi.nlm.nih.gov/pubmed/34793838
http://dx.doi.org/10.1016/j.jbc.2021.101418