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The mGluR6 ligand-binding domain, but not the C-terminal domain, is required for synaptic localization in retinal ON-bipolar cells
Signals from retinal photoreceptors are processed in two parallel channels—the ON channel responds to light increments, while the OFF channel responds to light decrements. The ON pathway is mediated by ON type bipolar cells (BCs), which receive glutamatergic synaptic input from photoreceptors via a...
Autores principales: | Agosto, Melina A., Adeosun, Abiodun Adefola R., Kumar, Nitin, Wensel, Theodore G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671642/ https://www.ncbi.nlm.nih.gov/pubmed/34793838 http://dx.doi.org/10.1016/j.jbc.2021.101418 |
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