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Inflammation-induced PELP1 expression promotes tumorigenesis by activating GM-CSF paracrine secretion in the tumor microenvironment

The inflammatory tumor microenvironment has been implicated as a major player fueling tumor progression and an enabling characteristic of cancer, proline, glutamic acid, and leucine-rich protein 1 (PELP1) is a novel nuclear receptor coregulator that signals across diverse signaling networks, and its...

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Detalles Bibliográficos
Autores principales: Vuttaradhi, Veena Kumari, Ezhil, Inemai, Ramani, Divya, Kanumuri, Rahul, Raghavan, Swetha, Balasubramanian, Vaishnavi, Saravanan, Roshni, Kanakarajan, Archana, Joseph, Leena Dennis, Pitani, Ravi Shankar, Sundaram, Sandhya, Sjolander, Anita, Venkatraman, Ganesh, Rayala, Suresh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671644/
https://www.ncbi.nlm.nih.gov/pubmed/34774800
http://dx.doi.org/10.1016/j.jbc.2021.101406