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The strength of corticomotoneuronal drive underlies ALS split phenotypes and reflects early upper motor neuron dysfunction
BACKGROUND: Split phenotypes, (split hand, elbow, leg, and foot), are probably unique to ALS, and are characterized by having a shared peripheral input of both affected and unaffected muscles. This implies an anatomical origin rostral to the spinal cord, primarily within the cerebral cortex. Therefo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671797/ https://www.ncbi.nlm.nih.gov/pubmed/34710283 http://dx.doi.org/10.1002/brb3.2403 |