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Structural Analysis on the Severe Acute Respiratory Syndrome Coronavirus 2 Non-structural Protein 13 Mutants Revealed Altered Bonding Network With TANK Binding Kinase 1 to Evade Host Immune System

Mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have made this virus more infectious. Previous studies have confirmed that non-structural protein 13 (NSP13) plays an important role in immune evasion by physically interacting with TANK binding kinase 1 (TBK1) to inhibit IFNβ...

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Detalles Bibliográficos
Autores principales: Rashid, Farooq, Suleman, Muhammad, Shah, Abdullah, Dzakah, Emmanuel Enoch, Chen, Shuyi, Wang, Haiying, Tang, Shixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671833/
https://www.ncbi.nlm.nih.gov/pubmed/34925297
http://dx.doi.org/10.3389/fmicb.2021.789062