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CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

BACKGROUND: The century-old Mycobacterium bovis Bacillus Calmette-Guerin (BCG) remains the only licensed vaccine against tuberculosis (TB). Despite this, there is still a lot to learn about the immune response induced by BCG, both in terms of phenotype and specificity. METHODS: We investigated immun...

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Detalles Bibliográficos
Autores principales: Singhania, Akul, Dubelko, Paige, Kuan, Rebecca, Chronister, William D., Muskat, Kaylin, Das, Jyotirmoy, Phillips, Elizabeth J., Mallal, Simon A., Seumois, Grégory, Vijayanand, Pandurangan, Sette, Alessandro, Lerm, Maria, Peters, Bjoern, Lindestam Arlehamn, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671872/
https://www.ncbi.nlm.nih.gov/pubmed/34902786
http://dx.doi.org/10.1016/j.ebiom.2021.103746