Cargando…
CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature
BACKGROUND: The century-old Mycobacterium bovis Bacillus Calmette-Guerin (BCG) remains the only licensed vaccine against tuberculosis (TB). Despite this, there is still a lot to learn about the immune response induced by BCG, both in terms of phenotype and specificity. METHODS: We investigated immun...
Autores principales: | Singhania, Akul, Dubelko, Paige, Kuan, Rebecca, Chronister, William D., Muskat, Kaylin, Das, Jyotirmoy, Phillips, Elizabeth J., Mallal, Simon A., Seumois, Grégory, Vijayanand, Pandurangan, Sette, Alessandro, Lerm, Maria, Peters, Bjoern, Lindestam Arlehamn, Cecilia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671872/ https://www.ncbi.nlm.nih.gov/pubmed/34902786 http://dx.doi.org/10.1016/j.ebiom.2021.103746 |
Ejemplares similares
-
The Challenge of Distinguishing Cell–Cell Complexes from Singlet Cells in Non‐Imaging Flow Cytometry and Single‐Cell Sorting
por: Burel, Julie G., et al.
Publicado: (2020) -
Lack of evidence for BCG vaccine protection from severe COVID-19
por: Lindestam Arlehamn, Cecilia S., et al.
Publicado: (2020) -
Classical CD4 T cells as the cornerstone of antimycobacterial immunity
por: Morgan, Jeffrey, et al.
Publicado: (2021) -
Quantitative and Qualitative Perturbations of CD8(+) MAITs in Healthy Mycobacterium tuberculosis–Infected Individuals
por: Pomaznoy, Mikhail, et al.
Publicado: (2020) -
Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis
por: Hillman, Hannah, et al.
Publicado: (2023)