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Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice

BACKGROUND: Innate immune responses to influenza A virus (IAV) infection are initiated in part by toll-like receptor 3 (TLR3). TLR3-dependent signaling induces an antiviral immune response and an NFκB-dependent inflammatory response. Protease-activated receptor 2 (PAR2) inhibits the antiviral respon...

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Detalles Bibliográficos
Autores principales: Gunther, Randall C., Bharathi, Vanthana, Miles, Stephen D., Tumey, Lauryn R., Schmedes, Clare M., Tatsumi, Kohei, Bridges, Meagan D., Martinez, David, Montgomery, Stephanie A., Beck, Melinda A., Camerer, Eric, Mackman, Nigel, Antoniak, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671937/
https://www.ncbi.nlm.nih.gov/pubmed/34925374
http://dx.doi.org/10.3389/fimmu.2021.791017