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Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice
BACKGROUND: Innate immune responses to influenza A virus (IAV) infection are initiated in part by toll-like receptor 3 (TLR3). TLR3-dependent signaling induces an antiviral immune response and an NFκB-dependent inflammatory response. Protease-activated receptor 2 (PAR2) inhibits the antiviral respon...
Autores principales: | Gunther, Randall C., Bharathi, Vanthana, Miles, Stephen D., Tumey, Lauryn R., Schmedes, Clare M., Tatsumi, Kohei, Bridges, Meagan D., Martinez, David, Montgomery, Stephanie A., Beck, Melinda A., Camerer, Eric, Mackman, Nigel, Antoniak, Silvio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671937/ https://www.ncbi.nlm.nih.gov/pubmed/34925374 http://dx.doi.org/10.3389/fimmu.2021.791017 |
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