A bispecific antibody targeting HER2 and PD-L1 inhibits tumor growth with superior efficacy

Activation of the programmed cell death protein 1 and programmed cell death ligand 1 (PD-1/PD-L1) signaling axis plays important roles in intrinsic or acquired resistance to human epidermal growth factor receptor 2 (HER2)-directed therapies in the clinic. Therefore, therapies simultaneously targetin...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Li, Cui, Yue, Liu, Xinyuan, Liu, Guojian, Dong, Xingchen, Tang, Lei, Hung, Yifeng, Wang, Chunhe, Feng, Mei-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671946/
https://www.ncbi.nlm.nih.gov/pubmed/34798072
http://dx.doi.org/10.1016/j.jbc.2021.101420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671946/
https://www.ncbi.nlm.nih.gov/pubmed/34798072
http://dx.doi.org/10.1016/j.jbc.2021.101420

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