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A bispecific antibody targeting HER2 and PD-L1 inhibits tumor growth with superior efficacy

Activation of the programmed cell death protein 1 and programmed cell death ligand 1 (PD-1/PD-L1) signaling axis plays important roles in intrinsic or acquired resistance to human epidermal growth factor receptor 2 (HER2)-directed therapies in the clinic. Therefore, therapies simultaneously targetin...

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Detalles Bibliográficos
Autores principales:	Chen, Yi-Li, Cui, Yue, Liu, Xinyuan, Liu, Guojian, Dong, Xingchen, Tang, Lei, Hung, Yifeng, Wang, Chunhe, Feng, Mei-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671946/ https://www.ncbi.nlm.nih.gov/pubmed/34798072 http://dx.doi.org/10.1016/j.jbc.2021.101420

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